Made to order
Elamipretide, cardiolipin-targeted tetrapeptide
SS-31 (Elamipretide) 10 mg
A tetrapeptide with the unusual property of accumulating selectively in the inner mitochondrial membrane, where it binds cardiolipin. It is one of the few compounds in this category with completed phase 3 clinical trials.
- CAS
- 736992-21-5
- Formula
- C32H49N9O5
- Molecular weight
- 639.8 g/mol
- Purity
- ≥ 98% verified by HPLC
- Presentation
- Amber glass vial with lyophilized powder, vacuum sealed.
- Includes 3 ml BAC waterIn the same box, at no cost.
$130 USD
How it works
- Binds cardiolipin and stabilises the architecture of the mitochondrial cristae.
- Improves the efficiency of the electron transport chain.
- Reduces reactive oxygen species production in the mitochondrion.
Qué dice la evidencia
- Dose-escalation trial in primary mitochondrial myopathy with improvement in the walk test.
Route described in the studies
- Route
- Subcutaneous daily.
- Preparation
- Reconstitute with BAC WATER without shaking.
- Application site
- Alternate the site with each application.
Documented effects
- Application site reaction, the most frequent in the trials
- Headache
- Nausea
When it is not used
- Pregnancy and breastfeeding
Storage
- Lyophilised
- 2 to 8 °C protected from light.
- Reconstituted
- 2 to 8 °C, within 21 days.
- Shipping
- Stable at ambient temperature in lyophilized form.
Research use only
Este compuesto se vende únicamente para investigación de laboratorio y desarrollo analítico. No es un medicamento, no está aprobado por ninguna autoridad sanitaria, y no se vende para diagnosticar, tratar, curar ni prevenir ninguna enfermedad. No es apto para consumo humano ni animal.