BAC WATER 3ml

Sterile water with 0.9% benzyl alcohol as a preservative. That is the whole difference from plain sterile water, and it is the one that matters: the preservative lets the stopper be pierced several times without the contents becoming contaminated, which is exactly what is needed when a compound vial is reconstituted and used over several weeks. It is the diluent used to prepare almost every compound in the catalogue.

Purity: Water for injection, pharmacopoeia grade
Presentation: Glass vial with a pierceable multi-dose rubber stopper.

$30 USD

How it works

The benzyl alcohol inhibits bacterial growth in the vial once the stopper has been pierced.
It maintains sterility across successive uses, not at the moment of the first draw.
It plays no part in the activity of the compound being reconstituted: it only dissolves and preserves it.

Qué dice la evidencia

0.9% benzyl alcohol is the recognised preservative for multi-dose injectable preparations.
Contraindicated in neonates because of its association with gasping syndrome.

Route described in the studies

Route: It is not administered on its own. It is the diluent used to reconstitute a lyophilized compound.
Preparation: Draw the calculated volume and direct the stream against the wall of the compound vial, never straight onto the powder. Swirl gently until fully dissolved; do not shake.
Application site: Not applicable.

Documented effects

Transient stinging at the application site, attributable to the preservative
Hypersensitivity reaction to benzyl alcohol, infrequent

When it is not used

Neonates and infants: benzyl alcohol is associated with gasping syndrome
Known hypersensitivity to benzyl alcohol
Not to be used as a diluent for compounds that require preservative-free sterile water, or those that require acetic acid

Storage

Lyophilised: Not applicable: the product is a liquid. Store at 20 to 25 °C, protected from light.
Reconstituted: Once the stopper has been pierced, use within 28 days. Refrigeration is not needed while unopened.
Shipping: Stable at ambient temperature. Do not freeze.

Preguntas frecuentes

Can I use plain sterile water instead?

For a single draw, yes. For a vial you will draw from several times, no: without a preservative every piercing of the stopper is a chance for contamination, and the solution stops being safe within days.

How much is needed per vial?

It depends on the concentration you are after, and the calculator settles that: give it the milligrams in the vial and the dose, and it returns the diluent volume and the exact mark on the syringe.

Does it work for fragment 176-191?

No. That compound does not dissolve well at neutral pH and needs dilute acetic acid. With water alone, undissolved particles remain and the real dose stops being the calculated one.

Research use only

Este compuesto se vende únicamente para investigación de laboratorio y desarrollo analítico. No es un medicamento, no está aprobado por ninguna autoridad sanitaria, y no se vende para diagnosticar, tratar, curar ni prevenir ninguna enfermedad. No es apto para consumo humano ni animal.