Made to order
Synthetic analogue of the ACTH 4-10 fragment with a Pro-Gly-Pro extension
Semax 10 mg
A heptapeptide derived from an ACTH fragment that has no hormonal activity. The Pro-Gly-Pro extension protects it from degradation and prolongs its action. It is registered as a medicine in Russia for stroke.
- CAS
- 80714-61-0
- Formula
- C37H51N9O10S
- Molecular weight
- 813.9 g/mol
- Purity
- ≥ 98% verified by HPLC
- Presentation
- Amber glass vial with lyophilized powder, vacuum sealed.
- Includes 3 ml BAC waterIn the same box, at no cost.
$120 USD
How it works
- Increases BDNF and NGF expression in hippocampus and cortex.
- Modulates the dopaminergic and serotonergic systems.
- Neuroprotective activity in cerebral ischaemia models.
- Does not retain the hormonal activity of the parent fragment.
Qué dice la evidencia
- Review of the heptapeptide's neuroprotective and nootropic activity.
Route described in the studies
- Route
- Subcutaneous, the route the lyophilised vial supports. Most of the literature used intranasal formulations, which are not what is supplied.
- Preparation
- Reconstitute with BAC WATER against the vial wall, without shaking.
- Application site
- Studies alternate the application site with each dose.
Documented effects
- Nasal irritation in the intranasal studies
- Mild headache
- Insomnia if applied late in the day
When it is not used
- Anxiety disorder in acute crisis
- Pregnancy and breastfeeding
Storage
- Lyophilised
- 2 to 8 °C protected from light.
- Reconstituted
- 2 to 8 °C, within 30 days.
- Shipping
- Stable at ambient temperature in lyophilized form.
Research use only
Este compuesto se vende únicamente para investigación de laboratorio y desarrollo analítico. No es un medicamento, no está aprobado por ninguna autoridad sanitaria, y no se vende para diagnosticar, tratar, curar ni prevenir ninguna enfermedad. No es apto para consumo humano ni animal.