Made to order
Dual agonist of the GIP and GLP-1 receptors
Tirzepatide 5 mg
A single molecule that activates two incretin receptors at once. The GIP component, absent from single agonists, changes the satiety response and lipid handling, which explains the differences seen against semaglutide in head-to-head comparison.
- CAS
- 2023788-19-2
- Formula
- C225H348N48O68
- Molecular weight
- 4813.5 g/mol
- Purity
- ≥ 98% verified by HPLC
- Presentation
- Amber glass vial with lyophilized powder, vacuum sealed.
- Includes 3 ml BAC waterIn the same box, at no cost.
$130 USD
How it works
- GIP receptor agonism, which enhances glucose-dependent insulin secretion.
- GLP-1 receptor agonism, with slowed gastric emptying and central satiety.
- Fatty acid acylation that allows weekly application.
Qué dice la evidencia
- Mean weight reduction of up to 20.9% at 72 weeks on the high dose.
- Superiority over semaglutide 1 mg in glycaemic control and weight.
Route described in the studies
- Route
- Subcutaneous weekly in the abdomen, thigh or arm.
- Preparation
- Reconstitute with BAC WATER against the vial wall, without shaking. Check the volume at every step change.
- Application site
- Rotate the site week to week.
Documented effects
- Nausea, diarrhoea and vomiting, especially when stepping up
- Loss of lean mass if protein intake is not sustained
- Reduced appetite that can compromise hydration
When it is not used
- Personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2
- Previous pancreatitis
- Concomitant use of another incretin agonist
- Pregnancy and breastfeeding
Storage
- Lyophilised
- 2 to 8 °C protected from light. Stable up to 24 months unopened.
- Reconstituted
- 2 to 8 °C. Use within 30 days. Do not freeze.
- Shipping
- Stable at ambient temperature in lyophilized form during shipping.
Preguntas frecuentes
How does it differ from semaglutide?
It adds GIP receptor agonism. In head-to-head comparison it produced greater reduction in weight and glycated haemoglobin, with a similar gastrointestinal profile.
Research use only
Este compuesto se vende únicamente para investigación de laboratorio y desarrollo analítico. No es un medicamento, no está aprobado por ninguna autoridad sanitaria, y no se vende para diagnosticar, tratar, curar ni prevenir ninguna enfermedad. No es apto para consumo humano ni animal.